Singles
Seeds
- Canada Félix Auger-Aliassime (quarterfinals, withdrew)
- United Kingdom Cameron Norrie
- United States Tommy Paul (quarterfinals)
- Argentina Francisco Cerúndolo
- Serbia Miomir Kecmanović (second round)
- Argentina Sebastián Báez (quarterfinals)
- France Richard Gasquet (first round)
- xxxxxxxxxxxxxxxxxxxxxxxxxxxxxUnited States Brandon Nakashima
vs.
Doubles
Seeds
- United States Rajeev Ram / United Kingdom Joe Salisbury
- Argentina Máximo González / Argentina Andrés Molteni (first round)
- France Nicholas Mahut / Netherlands Matwé Middelkoop
- Belgium Sander Gillé / Belgium Joran Vliegen (quarterfinals)
United States Rajeev Ram / United Kingdom Joe Salisbury vs. France /
2022 ATP Lyon Open Draws
Champions
Singles
United Kingdom Cameron Norrie def. Slovakia Alex Molčan, 6–3, 6–7(3–7), 6–1
Doubles
Croatia Ivan Dodig / United States Austin Krajicek def. Argentina Máximo González / Brazil Marcelo Melo, 6–3, 6–4
2021 ATP Lyon Open Draws
Champions
Singles
Greece Stefanos Tsitsipas def. United Kingdom Cameron Norrie, 6–3, 6–3
Doubles
Monaco Hugo Nys / Germany Tim Pütz def. France Pierre-Hugues Herbert / France Nicolas Mahut, 6–4, 5–7, [10–8]
2019 Lyon Open Draw
Singles
France Benoît Paire defeated Canada Félix Auger-Aliassime, 6–4, 6–3
Doubles
Croatia Ivan Dodig / France Édouard Roger-Vasselin defeated United Kingdom Ken Skupski / United Kingdom Neal Skupski, 6–4, 6–3
2018 Lyon Open Tennis Champions
Singles
Austria Dominic Thiem def. France Gilles Simon, 3–6, 7–6(7–1), 6–1
Doubles
Australia Nick Kyrgios / United States Jack Sock def. Czech Republic Roman Jebavý / Netherlands Matwé Middelkoop, 7–5, 2–6, [11–9]
2017 Lyon Open Tennis Champions
Singles
France Jo-Wilfried Tsonga def. Czech Republic Tomáš Berdych, 7–6(7–2), 7–5
Doubles
Argentina Andrés Molteni / Canada Adil Shamasdin def. New Zealand Marcus Daniell / Brazil Marcelo Demoliner, 6–3, 3–6, [10–5]